The role of the pseudoexfoliative syndrome as a transitional entity to glaucoma

The balance between the secretion of aqueous humor by ciliary body and its drainage through 2 independent pathways, trabecular meshwork uveoscleral outflow pathway; this will determine intraocular pressure, which is considered determining factor for glaucoma. Glaucoma an entity great clinical importance, being second cause blindness worldwide. There are different explanations pathophysiology disease, as well immunological vascular factors that lead to increase in causing all these trigger development Pseudoexfoliation syndrome can be defined a systemic pathology generated deposition extracellular fibrillar material tissues, which, depending on affected person, subsequent entities. progression sequelae may more related higher pressures than other mechanisms. Various studies relate oxidative stress glaucomatous progression. As composition pseudoexfoliation further studied, influence eye better understood.